Document Detail

Short- and long-term association between uric acid and a natural disaster.
MedLine Citation:
PMID:  9088046     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: This paper analyzes the longitudinal relationship between serum uric acid level and a natural disaster. METHODS: The sample consists of factory workers who were participating in a longitudinal epidemiological study of coronary heart disease risk factors. Participants were seen in 1975 (baseline), 1980 (5 year follow-up), and 1987 (12 year follow-up). The 5 year (1980) follow-up examination was interrupted by a major earthquake and resumed 2 weeks after the quake. At this examination, participants seen after the quake had, on the average, significantly lower serum uric acid than those seen before the earthquake. In 1987 (7 years after the quake), participants were questioned whether or not (in their own perception) they were still suffering from damages due to the 1980 earthquake. RESULTS: At the examination in 1987, participants who reported suffering from damage due to the 1980 quake showed on the average significantly increased serum uric acid compared with participants who reported not suffering from damages due to the 1980 quake. The analyses of the data of 578 individuals who participated in all three examinations confirmed these findings and showed that they were independent from levels of uric acid measured prior to the disaster. CONCLUSIONS: The reason for this apparent different association with uric acid and acute and long-term exposure to the quake remains to be clarified but these findings are consistent with the existence of diverse patterns of physiologic response to different stressors.
M Trevisan; E O'Leary; E Farinaro; F Jossa; R Galasso; E Celentano; A Scottoni; G Fusco; S Panico
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Psychosomatic medicine     Volume:  59     ISSN:  0033-3174     ISO Abbreviation:  Psychosom Med     Publication Date:    1997 Mar-Apr
Date Detail:
Created Date:  1997-06-12     Completed Date:  1997-06-12     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0376505     Medline TA:  Psychosom Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  109-13     Citation Subset:  IM    
Department of Social and Preventive Medicine, State University of New York at Buffalo 14214, USA.
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MeSH Terms
Adaptation, Psychological / physiology
Arousal / physiology
Coronary Disease / physiopathology
Follow-Up Studies
General Adaptation Syndrome / physiopathology*,  psychology
Heart Rate / physiology
Longitudinal Studies
Middle Aged
Risk Factors
Stress Disorders, Post-Traumatic / physiopathology,  psychology
Uric Acid / blood*
Grant Support
Reg. No./Substance:
69-93-2/Uric Acid
Comment In:
Psychosom Med. 1997 Mar-Apr;59(2):142-3   [PMID:  9088049 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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