| Short latency trigemino-sternocleidomastoid response in patients with migraine. | |
| | |
MedLine Citation:
|
PMID: 12796836 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To investigate the central trigeminal circuits in migraine patients. MATERIALS AND METHODS: Short latency responses can be recorded in sternocleidomastoid (SCM) muscles after stimulation of the trigeminal nerve (trigemino-cervical reflex). This brainstem reflex was investigated in 20 healthy subjects, in 20 patients suffering from migraine with aura (MWA) and in 20 patients suffering from migraine without aura (MWOA) during and between the attacks. RESULTS: The trigemino-cervical responses were bilaterally abnormal in 17 patients with MWA and 15 patients with MWOA during the headache attacks, in 11 patients with MWA and in 10 patients with MWOA during the interictal period. In the patients with normal trigemino-cervical responses during the pain-free phase the triptan was significantly more effective at relieving headache. CONCLUSIONS: Our findings further support and emphasise the role of the trigeminal system in the pathogenesis of migraine. The bilateral location of the abnormalities suggests a centrally located dysfunction. Therefore, the trigemino-cervical reflex is sensitive in disclosing a disturbed brainstem activity and may be an index of neuronal activity in the human brainstem; moreover their assessment may help as valuable prognostic tool for predicting the efficacy of triptans therapy. |
| | |
Authors:
|
Raffaele Nardone; Frediano Tezzon |
Related Documents
:
|
23417226 - Usefulness of scintigraphy to predict electrical storms in severe idiopathic dilated ca... 1324986 - Baclofen-assisted detoxification from opiates. a pilot study. 9755306 - Headache and chiari i malformation in the pediatric population. 17493416 - Penetrating head injury in planned and repetitive deliberate self-harm. 10197736 - Studies on the function of the checkerboard pattern stimulator: analysis of ocular posi... 9766536 - The use of ultrasonography as a diagnostic tool for superficial fascial space infections. |
Publication Detail:
|
Type: Clinical Trial; Comparative Study; Journal Article |
Journal Detail:
|
Title: Journal of neurology Volume: 250 ISSN: 0340-5354 ISO Abbreviation: J. Neurol. Publication Date: 2003 Jun |
Date Detail:
|
Created Date: 2003-06-10 Completed Date: 2003-08-27 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0423161 Medline TA: J Neurol Country: Germany |
Other Details:
|
Languages: eng Pagination: 725-32 Citation Subset: IM |
Affiliation:
|
Dept. of Neurology, F. Tappeiner Hospital, Via Rossini, 5, 39012 Merano, BZ, Italy. raffaele.nardone@asbmeran-o.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Analysis of Variance Brain Stem / physiopathology* Case-Control Studies Double-Blind Method Electric Stimulation Electromyography / methods Epilepsy / physiopathology Female Functional Laterality Humans Male Middle Aged Migraine Disorders / physiopathology* Neck Muscles / innervation* Reaction Time / physiology* Reflex / physiology* Trigeminal Nerve / physiopathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Chronic dysimmune neuropathy. A subclassification based upon the clinical features of 102 patients.
Next Document: Frontotemporal dementia and parkinsonism with the P301S tau gene mutation in a Jewish family.