Document Detail

Short interpregnancy interval and the risk of disabling cerebral palsy in a low birth weight population.
MedLine Citation:
PMID:  9602192     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The objective of this study was to investigate the relation of short interpregnancy interval and cerebral palsy (CP) in a low birth weight population in whom neonatal brain injury was systematically ascertained in the newborn period. STUDY DESIGN: We used data from a prospective cohort study of 1105 infants born < or = 2000 gm, designed to study the cause and consequences of neonatal brain injury. Of the 777 children with data on brain injury and CP, 382 were born to multiparous women, and 375 had information available to calculate interpregnancy interval, defined as the number of days from the end of the last pregnancy to conception of the index pregnancy. RESULTS: In the presence of the strong explanatory power of neonatal brain injury, short interpregnancy interval maintains an independent risk for disabling CP. CONCLUSION: In this cohort of low birth weight infants, short interpregnancy interval appears to represent a significant risk for the development of disabling CP.
J A Pinto-Martin; A Cnaan; H Zhao
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  132     ISSN:  0022-3476     ISO Abbreviation:  J. Pediatr.     Publication Date:  1998 May 
Date Detail:
Created Date:  1998-06-18     Completed Date:  1998-06-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  818-21     Citation Subset:  AIM; IM    
University of Pennsylvania School of Nursing 19104, USA.
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MeSH Terms
Birth Intervals*
Brain Injuries / complications*,  ultrasonography
Cerebral Palsy / etiology*
Cohort Studies
Educational Status
Gestational Age
Infant, Low Birth Weight*
Infant, Newborn
Logistic Models
Predictive Value of Tests
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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