Document Detail

Short communication: Fluoroquinolone susceptibility of Staphylococcus aureus strains isolated from caprine clinical mastitis in southeast Spain.
MedLine Citation:
PMID:  20965339     Owner:  NLM     Status:  MEDLINE    
The antibiotic susceptibility of 32 strains of Staphylococcus aureus isolated from the mastitic milk of dairy goats was evaluated. The antibiotics tested were 3 fluoroquinolones that have been developed especially for use in veterinary medicine: danofloxacin, marbofloxacin, and orbifloxacin. Minimum inhibitory concentration (MIC) tests were performed according to the microdilution broth method. The MIC(90) (concentration at which 90% inhibition is achieved) values obtained were 0.5, 1, and 1 mg/L for danofloxacin, marbofloxacin, and orbifloxacin, respectively. Danofloxacin was the most active fluoroquinolone tested against Staph. aureus strains isolated from milk; however, specific testing is required before using these drugs as therapy for the control of clinical mammary infections in goats.
P Marín; E Escudero; E Fernández-Varón; C M Cárceles; J C Corrales; A Gómez-Martín; I Martínez
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of dairy science     Volume:  93     ISSN:  1525-3198     ISO Abbreviation:  J. Dairy Sci.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-22     Completed Date:  2011-01-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985126R     Medline TA:  J Dairy Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5243-5     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.
Department of Pharmacology, Faculty of Veterinary Medicine, University of Murcia, Murcia, Spain.
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MeSH Terms
Anti-Bacterial Agents / pharmacology*
Ciprofloxacin / analogs & derivatives,  pharmacology
Fluoroquinolones / pharmacology*
Goat Diseases / microbiology*
Mastitis / microbiology,  veterinary*
Microbial Sensitivity Tests / veterinary
Milk / microbiology*
Staphylococcus aureus / drug effects*,  isolation & purification
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Fluoroquinolones; 0/orbifloxacin; 112398-08-0/danofloxacin; 115550-35-1/marbofloxacin; 85721-33-1/Ciprofloxacin

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