Document Detail


Short arm dicentric Y chromosome with associated statural defects in a sterile man.
MedLine Citation:
PMID:  2427435     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A short arm dicentric Y chromosome is described as the predominant cell line in a sterile man. The patient also presents with short stature. Tooth development appears normal. Only Sertoli cells are present in the seminiferous tubules. It is suggested that the function of the gene controlling spermatogenesis in Yq11 in man might be to prevent proliferation or migration of germ cells to the gonad of the early embryo.
Authors:
A C Chandley; P Ambros; S McBeath; T B Hargreave; F Kilanowski; G Spowart
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Human genetics     Volume:  73     ISSN:  0340-6717     ISO Abbreviation:  Hum. Genet.     Publication Date:  1986 Aug 
Date Detail:
Created Date:  1986-10-02     Completed Date:  1986-10-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7613873     Medline TA:  Hum Genet     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  350-3     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Centromere*
Chromosome Aberrations*
Chromosome Banding
Chromosomes*
Growth Disorders / genetics*
Humans
Infertility, Male / genetics*
Karyotyping
Male
Staining and Labeling
Testis / pathology
Y Chromosome*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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