| Short-Term Effect of Cryotherapy on Human Scleral Tissue by Atomic Force Microscopy. | |
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MedLine Citation:
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PMID: 23225601 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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This study investigated the inflammatory effect of cryotherapy application on collagen matrix network in human infant sclera. Donor scleral tissues taken from three infant patients divided into five groups: control group, sham-treated group, and three cryotreated groups. In the cryotherapy groups, the sclera was treated for 5 s, 10 s, and 20 s with -80°C freezing by a cryosurgical system. The cryotreated reactions were examined using double histological analysis with hematoxylin-eosin and Masson's trichrome, and atomic force microscopy analysis to quantify the diameter and D-banding of collagen fibrils. The infant scleral tissues treated with cryotherapy showed a significantly increased collagen density associated with inflammatory response (p < 0.05), increased fibril diameter (p < 0.005) compared to the scleral tissues in the control group. The results directly suggest that the cryotherapy affects the morphology of scleral collagen. SCANNING 00: 1-6, 2012. © Wiley Periodicals, Inc. |
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Authors:
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Seung Jun Lee; Samjin Choi; Moo Sang Kim; Youjin Cheong; Hyung-Woo Kwak; Hun-Kuk Park; Kyung-Hyun Jin |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-12-5 |
Journal Detail:
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Title: Scanning Volume: - ISSN: 1932-8745 ISO Abbreviation: Scanning Publication Date: 2012 Dec |
Date Detail:
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Created Date: 2012-12-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7903371 Medline TA: Scanning Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© Wiley Periodicals, Inc. |
Affiliation:
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Department of Ophthalmology, Kyung Hee University, Seoul, Korea. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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