| Short QT interval in clinical practice. | |
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MedLine Citation:
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PMID: 20667544 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The last ten years have seen a growing interest in clinical scenarios, where a short QT interval may play a role, especially because of an increased risk of sudden cardiac death in some situations. One such entity is Short QT Syndrome, which has emerged as a rare, but very malignant disease, in particular when the QT interval is very short. A short QT interval has also been noticed in some patients with other arrhythmic syndromes such as Idiopathic Ventricular Fibrillation, Brugade Syndrome and Early Repolarization Syndrome, but the role of a short QT interval in these settings is so far not known. Hypercalcemia often leads to shortening of the QT interval, but there are no data in humans to suggest an increased risk of sudden cardiac death in this setting. In addition, a shorter-than-usual QT interval has been reported in patients with Chronic Fatigue Syndrome and in response to atropine, catecholamine and Hyperthermia. When a short QT interval is encountered in daily clinical practice, these various scenarios needs to be considered, but it is still not possible to come up with clear guidelines for how to work up and risk stratify such individuals. Genetic testing is only useful in very few and the value of an electrophysiologic study, Holter monitoring or stress testing to assess QT adaptation to heart rate and T wave morphology analysis may all be helpful, but not well-established, tests in this setting. |
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Authors:
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Preben Bjerregaard; Hari Nallapaneni; Ihor Gussak |
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Publication Detail:
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Type: Journal Article; Review Date: 2010-07-27 |
Journal Detail:
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Title: Journal of electrocardiology Volume: 43 ISSN: 1532-8430 ISO Abbreviation: J Electrocardiol Publication Date: 2010 Sep-Oct |
Date Detail:
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Created Date: 2010-08-23 Completed Date: 2011-01-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0153605 Medline TA: J Electrocardiol Country: United States |
Other Details:
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Languages: eng Pagination: 390-5 Citation Subset: IM |
Copyright Information:
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Published by Elsevier Inc. |
Affiliation:
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Division of Cardiology, VA Medical Center and Washington University in St. Louis, St. Louis, MO 63106, USA. preben.bjerregaard@va.gov |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Arrhythmias, Cardiac
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complications,
diagnosis*,
genetics,
physiopathology Death, Sudden, Cardiac / etiology Electrocardiography Electrophysiologic Techniques, Cardiac Genetic Testing Humans Risk Assessment Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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