Document Detail

Short- and Long-term Prognosis of Previous and New-onset Atrial Fibrillation in ST-segment Elevation Acute Myocardial Infarction.
MedLine Citation:
PMID:  25125324     Owner:  NLM     Status:  Publisher    
INTRODUCTION AND OBJECTIVES: The impact of atrial fibrillation on the prognosis of myocardial infarction is still the subject of debate. We analyzed the influence of previous and new-onset atrial fibrillation on in-hospital and long-term prognosis in patients with acute myocardial infarction.
METHODS: Prospective study of 4284 patients with ST-segment elevation acute myocardial infarction. We studied all-cause in-hospital and long-term mortality (median, 7.2 years) using adjusted models.
RESULTS: In total, 3.2% of patients had previous atrial fibrillation and 9.8% had new-onset atrial fibrillation. In general, both groups of patients had a high baseline risk profile and an increased likelihood of in-hospital complications. The crude in-hospital mortality rate was higher in patients with previous atrial fibrillation than in those with new-onset atrial fibrillation (22% vs 12%; P<.001; 30% vs 10%; P<.001). The long-term mortality rate was 11.11/100 patient-years in patients with previous atrial fibrillation and 5.35/100 patient years in those with new-onset atrial fibrillation (both groups, P<.001). New-onset fibrillation alone (odds ratio=1.55; 95% confidence interval, 1.08-2.22) was an independent predictor of in-hospital mortality. Previous atrial fibrillation (hazard ratio=1.24; 95% confidence interval, 0.94-1.64) and new-onset atrial fibrillation (hazard ratio=0.98; 95% confidence interval, 0.80-1.21) were not independent predictors of long-term mortality.
CONCLUSIONS: New-onset atrial fibrillation during hospitalization is an independent risk factor for in-hospital mortality in acute myocardial infarction. Full English text available
Luciano Consuegra-Sánchez; Antonio Melgarejo-Moreno; José Galcerá-Tomás; Nuria Alonso-Fernández; Angela Díaz-Pastor; Germán Escudero-García; Leticia Jaulent-Huertas; Marta Vicente-Gilabert
Related Documents :
24071004 - Bp control and left ventricular hypertrophy regression in children with ckd.
24899474 - A simple angiographic index to predict adverse clinical outcome associated with acute m...
23611754 - Left ventricular diastolic function and long-term outcomes in patients with normal exer...
23328834 - Comparison of clinical features and outcomes of patients with acute myocardial infarcti...
10423664 - Controlling myocardial matrix remodeling: implications for heart failure.
2178374 - Cardiac glycosides and congestive heart failure.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-8-11
Journal Detail:
Title:  Revista espanola de cardiologia     Volume:  -     ISSN:  1579-2242     ISO Abbreviation:  Rev Esp Cardiol     Publication Date:  2014 Aug 
Date Detail:
Created Date:  2014-8-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404277     Medline TA:  Rev Esp Cardiol     Country:  -    
Other Details:
Languages:  ENG; SPA     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Sociedad Española de Cardiología. Publicado por Elsevier España. All rights reserved.
Vernacular Title:
Pronóstico a corto y largo plazo de la fibrilación auricular previa y de novo en pacientes con infarto agudo de miocardio con elevación del segmento ST.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  One-Pot Consecutive Catalysis by Integrating Organometallic Catalysis with Organocatalysis.
Next Document:  MRS water resonance frequency in childhood brain tumours: a novel potential biomarker of temperature...