Document Detail

Short- and Long-Term Prognostic Value of the TIMI Risk Score after Primary Percutaneous Coronary Intervention for ST-segment Elevation Myocardial Infarction.
MedLine Citation:
PMID:  22971136     Owner:  NLM     Status:  Publisher    
Objectives:  We investigated the short- and long-term predictive value of the TIMI risk score regarding mortality for patients treated with primary percutaneous coronary intervention (PPCI) for ST-elevation myocardial infarction (STEMI). Background:  Data on the long-term predictive value of the TIMI risk score is sparse. Methods:  We used data from 3,609 STEMI patients undergoing PPCI in a high-volume PCI center in The Netherlands. Cumulative event rates according to TIMI score variables were estimated with the Kaplan-Meier method and compared with the log-rank test. The original TIMI risk score was modified based on the availability of the data in the single center registry. Results:  Higher TIMI scores were associated with significantly higher mortality at short- and long-term follow-up (P < 0.001 for both). Age and Killip Class IV at presentation were significant predictors for both short- and long-term mortality. Patients with an anterior MI, heart frequence >100 beats per minute, or systolic blood pressure <100 mmHG had a worse short-term prognosis compared to those who had not. However, long-term mortality was nonsignificantly different. The presence of a history of diabetes/hypertension and weight had only long-term prognostic value. Time to PPCI did not have any prognostic value. Conclusions:  Our current report shows that the TIMI risk score has both short- and long-term discriminative value. The different variables contained in the TIMI risk score predict short-term prognosis, others predominantly long-term mortality, whereas some are predictive for both. (J Interven Cardiol 2012;**:1-6).
Peter Damman; Pier Woudstra; Wichert J Kuijt; Wouter J Kikkert; Tim P VAN DE Hoef; Maik J Grundeken; Ralf E Harskamp; Jose P S Henriques; Jan J Piek; Jan G P Tijssen; Robbert J DE Winter
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-12
Journal Detail:
Title:  Journal of interventional cardiology     Volume:  -     ISSN:  1540-8183     ISO Abbreviation:  J Interv Cardiol     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8907826     Medline TA:  J Interv Cardiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
©2012, Wiley Periodicals, Inc.
From the Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
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