| Shock wave lithotripsy is not predictive of hypertension among community stone formers at long-term followup. | |
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MedLine Citation:
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PMID: 21074794 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: Concern exists over the subsequent development of hypertension after shock wave lithotripsy for the treatment of symptomatic urolithiasis. Referral bias and lack of long-term followup have been limitations of prior studies. MATERIALS AND METHODS: We identified all Olmsted County, Minnesota residents with a diagnosis of urolithiasis from 1985 to 2008. The charts were electronically queried for hypertension and obesity by diagnostic codes, and use of shock wave lithotripsy by surgical codes. All patients first diagnosed with hypertension before or up to 90 days after the first documented kidney stone were considered to have prevalent hypertension and were excluded from analysis. Cox proportional hazards models were used to assess the association of shock wave lithotripsy with a subsequent diagnosis of hypertension. RESULTS: We identified 6,077 patients with incident urolithiasis with more than 90 days of followup. We excluded 1,295 (21.3%) members of the population for prevalent hypertension leaving 4,782 patients with incident urolithiasis for analysis. During an average followup of 8.7 years new onset hypertension was diagnosed in 983 (20.6%) members of the cohort at a mean of 6.0 years from the index stone date. Only 400 (8.4%) patients in the cohort were treated with shock wave lithotripsy. There was no significant association between shock wave lithotripsy and the development of hypertension in univariate (p = 0.33) and multivariate modeling controlling for age, gender and obesity (HR 1.03; 95% CI 0.84, 1.27; p = 0.77). CONCLUSIONS: In a large population based cohort of kidney stone formers we failed to identify an association between shock wave lithotripsy and the subsequent long-term risk of hypertension. |
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Authors:
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Amy E Krambeck; Andrew D Rule; Xujian Li; Eric J Bergstralh; Matthew T Gettman; John C Lieske |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural Date: 2010-11-13 |
Journal Detail:
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Title: The Journal of urology Volume: 185 ISSN: 1527-3792 ISO Abbreviation: J. Urol. Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-12-14 Completed Date: 2011-01-06 Revised Date: 2012-04-23 |
Medline Journal Info:
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Nlm Unique ID: 0376374 Medline TA: J Urol Country: United States |
Other Details:
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Languages: eng Pagination: 164-9 Citation Subset: AIM; IM |
Copyright Information:
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Copyright © 2011 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Urology, Mayo Clinic School of Medicine, Rochester, Minnesota 55905, USA. Krambeck.amy@mayo.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Follow-Up Studies Humans Hypertension / etiology* Kidney Calculi / therapy Lithotripsy / adverse effects* Male Middle Aged Risk Factors Time Factors |
| Grant Support | |
ID/Acronym/Agency:
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DK83007/DK/NIDDK NIH HHS; K23 DK078229-05/DK/NIDDK NIH HHS; L30 DK084819-01/DK/NIDDK NIH HHS; R01 AG034656/AG/NIA NIH HHS; R01 AG034676/AG/NIA NIH HHS; R01 AG034676-45/AG/NIA NIH HHS |
| Comments/Corrections | |
Erratum In:
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J Urol. 2011 Mar;185(3):1161 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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