Document Detail


Shock induced electrical activation in structurally detailed models of pig left-ventricular tissue.
MedLine Citation:
PMID:  19964325     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Detailed models of sample specific structures in pig left-ventricular tissue have been constructed. These models include epicardial and endocardial surfaces, fiber and sheet orientations, vessels and cleavage planes with significant dimensions. This work shows that it is possible to extract from 3D tissue images reduced dimension descriptions of cleavage planes in the heart wall. These descriptions are used to analyze the response of tissue to electrical shocks of varying strengths. The presence of explicit discontinuities in the heart significantly reduces the time required for transmural activation and provides a basis for understanding successful defibrillation.
Authors:
Mark L Trew; Jesse L Ashton; Bryan J Caldwell; Bruce H Smaill
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference     Volume:  1     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2009  
Date Detail:
Created Date:  2009-12-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3948-51     Citation Subset:  IM    
Affiliation:
Auckland Bioengineering Institute, University of Auckland, New Zealand.
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