Document Detail

Shining light on materials--a self-sterilising revolution.
MedLine Citation:
PMID:  22819684     Owner:  NLM     Status:  MEDLINE    
This review focuses on the development of light activated antimicrobial surfaces. These surfaces kill microbes by the action of light and have potential applications in domestic and healthcare settings. The inspiration for the new self-cleaning surfaces originates from photodynamic therapy where light is used to locate and destroy tumours. The first generation photosensitiser molecules, based on a porphyrin ring structure, could be considered as bioinspired and chemically related to chlorophyll. The review looks at developments of both soft polymeric surfaces with either surface bound or impregnated photosensitiser molecules; and hard inorganic surfaces such as modified titanium dioxide. The bacterial kill mechanisms are looked into with both surface types showing primary microbial kill through a radical induced pathway. The hard inorganic surfaces also show low bacterial adherence by means of a light activated photo-wetting of the surfaces meaning that they are "Easy Clean" and wash off microbes uniformly.
Sacha Noimark; Charles W Dunnill; Ivan P Parkin
Related Documents :
20216664 - Intermittent characteristic curves for kodak 649f plates at 514.5 nm.
19165694 - Lipoic acid and 6-formylpterin reduce potentiation of noise-induced hearing loss by car...
20070214 - Metamorphosis delay in xenopus laevis (daudin) tadpoles exposed to a 50 hz weak magneti...
7809404 - Latent inhibition, context specificity, and context familiarity.
12364534 - Monitoring kinetic and frequency-domain properties of eyelid responses in mice with mag...
7975334 - Visual suppression and its effect upon color and luminance sensitivity.
Publication Detail:
Type:  Journal Article; Review     Date:  2012-07-20
Journal Detail:
Title:  Advanced drug delivery reviews     Volume:  65     ISSN:  1872-8294     ISO Abbreviation:  Adv. Drug Deliv. Rev.     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-05-06     Completed Date:  2013-09-27     Revised Date:  2014-02-20    
Medline Journal Info:
Nlm Unique ID:  8710523     Medline TA:  Adv Drug Deliv Rev     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  570-80     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier B.V. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Manufactured Materials*
Photosensitizing Agents
Sterilization / instrumentation*,  methods
Surface Properties
Grant Support
G0902208//Medical Research Council
Reg. No./Substance:
0/Photosensitizing Agents; 0/Polymers; 15FIX9V2JP/titanium dioxide; D1JT611TNE/Titanium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Disentangling sources of individual differences in diurnal salivary ?-amylase: Reliability, stabilit...
Next Document:  Dosimetry estimation on variations of patient size in prostate volumetric-modulated arc therapy.