Document Detail


Shifting the focus of attention modulates amygdala and anterior cingulate cortex reactivity to emotional faces.
MedLine Citation:
PMID:  22425719     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Functional neuroimaging studies have largely established the prominence of amygdala during emotion processing and prefrontal areas such as anterior cingulate cortex (ACC) during attentional modulation. In general, emotion processing paradigms known to probe amygdala have not been adapted to recruit prefrontal areas. In this study we used a well-known perceptual face matching paradigm, designed to elicit amygdala response, and asked volunteers to shift their focus in order to recruit regions responsible for attentional control. Stimuli comprised a trio of geometric shapes (circles, rectangles, triangles) presented alongside a trio of emotional faces (angry, fear, or happy) within the same field of view, and subjects were instructed to Match Faces or Match Shapes, as a means of attending to and away from the emotional content, respectively. We observed greater amygdala reactivity to Match Faces (>Match Shapes), and greater rostral ACC response to Match Shapes (>Match Faces). Results indicate that simply and volitionally directing attention toward or away from emotional content correspondingly modulates amygdala and ACC activity.
Authors:
Heide Klumpp; Mike Angstadt; K Luan Phan
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2012-03-08
Journal Detail:
Title:  Neuroscience letters     Volume:  514     ISSN:  1872-7972     ISO Abbreviation:  Neurosci. Lett.     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-04-05     Completed Date:  2012-09-14     Revised Date:  2014-09-24    
Medline Journal Info:
Nlm Unique ID:  7600130     Medline TA:  Neurosci Lett     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  210-3     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Adult
Amygdala / physiology*
Attention / physiology*
Emotions / physiology*
Facial Expression
Female
Functional Neuroimaging
Gyrus Cinguli / physiology*
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Imaging
Male
Grant Support
ID/Acronym/Agency:
K23 MH076198/MH/NIMH NIH HHS; K23 MH076198-01A1/MH/NIMH NIH HHS; K23MH076198/MH/NIMH NIH HHS; UL1 RR024986/RR/NCRR NIH HHS; UL1 RR024986-02/RR/NCRR NIH HHS; UL1RR024986/RR/NCRR NIH HHS
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