Document Detail


Shifting of the blood T:B lymphocyte ratio in myasthenia gravis patients after thymectomy.
MedLine Citation:
PMID:  301616     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The immunologic role of thymus in human adults is still unclear, in a high percentage of patients with myasthenia gravis, improvement of the disease follows thymectomy. The biologic basis of this phenomenon is also unknown. We found that patients thymectomized for more than 9 months have a low percentage of T cells (mean 34 percent). The mean T cell percentage in control myasthenia gravis patients is 52 percent. Patients thymectomized for more than 18 and 24 months exhibit values of T cell percentage not lower than those of patients thymectomized for more than 9 months. Our results may be interpreted according to a humoral action of the thymus in regulating the percentage of T lymphocytes.
Authors:
L Russo; C Scoppetta; P Tonali
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurology     Volume:  27     ISSN:  0028-3878     ISO Abbreviation:  Neurology     Publication Date:  1977 Jul 
Date Detail:
Created Date:  1977-08-12     Completed Date:  1977-08-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  642-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
B-Lymphocytes / immunology*
Cell Count
Female
Humans
Leukocyte Count
Male
Middle Aged
Myasthenia Gravis / immunology*,  surgery
T-Lymphocytes / immunology*
Thymectomy*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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