Document Detail


A Shell-Based Inverse Approach of Stress Analysis in Intracranial Aneurysms.
MedLine Citation:
PMID:  23392863     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Predicting pressure induced wall stress in intracranial aneurysms continues to be of interest for aneurysm safety assessment. In quasi-static analysis, there are two distinct approaches that one may take, the forward approach and the inverse approach. The inverse approach starts from a deformed configuration and thus is naturally suited to image-based, patient-specific analysis. Early studies by the authors' team suggested that the inverse approach, in the context of estimating the wall stress in cerebral aneurysms, depends weakly on the material description. In this article, we present a population study to further demonstrate the inverse method, in particular, the remarkable feature of insensitivity to material properties. Twenty-six aneurysm models derived from patient-specific images were employed in the study. Wall stresses were predicted in both the inverse and forward approaches using three material models. Results showed that, while forward computation yielded up to ~100% stress difference between some materials, the inverse solutions stayed close across materials. The inverse method, in addition to being methodologically accurate in dealing with pre-deformations, has the added convenience of insensitivity to uncertainties in wall tissue properties. New insight into the stress-geometry relation was also discussed.
Authors:
Jia Lu; Shouhua Hu; Madhavan L Raghavan
Related Documents :
17282863 - Evaluation of respiratory system models based on parameter estimates from impulse oscil...
8398523 - Solubility characteristics of the ideal agent for measurement of cardiac output by solu...
23166463 - An illustrated key to the genera and subgenera of the recent azooxanthellate scleractin...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-2-8
Journal Detail:
Title:  Annals of biomedical engineering     Volume:  -     ISSN:  1521-6047     ISO Abbreviation:  Ann Biomed Eng     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-2-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0361512     Medline TA:  Ann Biomed Eng     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Mechanical and Industrial Engineering, The University of Iowa, Iowa City, IA, 52242, USA, jialu@engineering.uiowa.edu.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Liver support systems: will they ever reach prime time?
Next Document:  Taurine, glutathione and bioenergetics.