Document Detail

Shear stress in cells generated by ultrasound.
MedLine Citation:
PMID:  16928394     Owner:  NLM     Status:  MEDLINE    
An experimental study using a mason horn of 21.4 kHz indicated that the threshold shear stress for cell sonoporation was 12+/-4 Pa for ultrasound exposure time up to 7 min. Numerical calculations have shown that shear stress associated with microstreaming surrounding encapsulated bubbles may be large enough to generate sonoporation at 0.1 MPa of 1 or 2 MHz ultrasound.
Junru Wu
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Publication Detail:
Type:  Journal Article; Review     Date:  2006-08-07
Journal Detail:
Title:  Progress in biophysics and molecular biology     Volume:  93     ISSN:  0079-6107     ISO Abbreviation:  Prog. Biophys. Mol. Biol.     Publication Date:    2007 Jan-Apr
Date Detail:
Created Date:  2006-12-01     Completed Date:  2007-02-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401233     Medline TA:  Prog Biophys Mol Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  363-73     Citation Subset:  IM    
Department of Physics, University of Vermont, Burlington, VT 05405, USA.
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MeSH Terms
Cell Membrane / physiology*,  radiation effects*
Cell Membrane Permeability / radiation effects*
Cell Survival / radiation effects
Computer Simulation
Jurkat Cells
Mechanotransduction, Cellular / physiology*,  radiation effects*
Models, Biological*
Phonophoresis / methods*
Radiation Dosage
Shear Strength
Stress, Mechanical

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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