Document Detail

Shadow cell differentiation in tumours of the colon and uterus.
MedLine Citation:
PMID:  7538784     Owner:  NLM     Status:  MEDLINE    
We report on six patients with tumours of visceral organs (three patients with endometrial adenocarcinoma with squamous cell differentiation, one patient with atypical hyperplasia of endometrium, and two patients with adenocarcinoma of the colon with squamous cell differentiation), where unquestionable differentiation into shadow cells was observed. In all six cases the shadow cells were found mostly in the morules of immature squamous cells. The shadow cells were morphologically identical, on the light microscopical and ultrastructural level, to similar cells found in pilomatricomas. They were often accompanied by granulomatous giant cell reaction and calcification.
M Zámecník; M Michal
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Zentralblatt für Pathologie     Volume:  140     ISSN:  0863-4106     ISO Abbreviation:  Zentralbl. Pathol.     Publication Date:  1995 Apr 
Date Detail:
Created Date:  1995-06-29     Completed Date:  1995-06-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9105594     Medline TA:  Zentralbl Pathol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  421-6     Citation Subset:  IM    
Department of Pathology, Regional Hospital, Trencín, Slovak Republic.
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MeSH Terms
Adenocarcinoma / pathology*,  ultrastructure
Carcinoma, Squamous Cell / pathology
Cell Differentiation
Colonic Neoplasms / pathology*
Endometrial Neoplasms / genetics*
Endometrium / pathology
Keratins / ultrastructure
Microscopy, Electron
Middle Aged
Uterine Neoplasms / pathology*
Uterus / pathology
Reg. No./Substance:

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