| Sezary syndrome--without erythroderma. | |
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MedLine Citation:
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PMID: 17656944 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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Sezary syndrome (SS), is described as the classical triad of pruritic erythroderma, lymphadenopathy, and presence of more than 10% of circulating Sezary cells in the peripheral blood. We report on unusual case of advanced cutaneous T - cell lymphoma with classical haematological and histopathological features of Sezary syndrome, but lacking the clinical features of erythroderma. A 66 year old man presented with asymptomatic multiple papules, plaques and nodules and with generalized lymphadenopathy. Peripheral smear showed more than 60% of Sezary cells. Skin and lymph node biopsy showed typical features of T-cell lymphoma and immunohistochemistry and CD marker studies showed the cells to be atypical T-lymphocytes. This unusual case is highlighted to denote that erythroderma need not be taken as a hard and fast criterion for diagnosing Sezary syndrome. |
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Authors:
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K Abdul Samad; Moorthy K Prasanna; Ali P Akhar |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Indian journal of dermatology, venereology and leprology Volume: 68 ISSN: 0973-3922 ISO Abbreviation: Indian J Dermatol Venereol Leprol Publication Date: 2002 Jul-Aug |
Date Detail:
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Created Date: 2007-07-27 Completed Date: 2007-08-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7701852 Medline TA: Indian J Dermatol Venereol Leprol Country: India |
Other Details:
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Languages: eng Pagination: 225-6 Citation Subset: - |
Affiliation:
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Department of Dermatology and Venereology Medical College, Trivandrum, Kerala, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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