| Sexual orientation, handedness, sex ratio and fetomaternal tolerance-rejection. | |
| | |
MedLine Citation:
|
PMID: 21249307 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Fraternal birth order (FBO) appears as a prenatal cause of 15% of homosexual males (gays) through mnemonic maternal anti-male factors. Non-right-handed men seem to be protected from homosexuality. Four hypotheses are proposed: (1) androgenic factors of non-right-handedness neutralize anti-male factors; (2) non-right-handedness and homosexuality are lethal or produce mental impairment; (3) non-right-handed male embryos are insensitive to anti-male factors; (4) mothers of non-right-handed fetuses do not produce anti-male factors. Studies of the sex ratio (SR) of older and younger siblings show: (1) a significant heterogeneity in the SR of siblings of right or non-right handed heterosexual men and women; (2) lesbians are born among siblings with high SR; (3) siblings of right-handed gays show a higher SR than non-right-handed gays that present a low SR. Based on our discovery of maternal tolerance-rejection processes, associated with genetic systems (ABO, Rh), where zygotes or embryos different from their mother induce better pregnancy and maternal tolerance than do those that share antigens with their mothers, I propose a new explanation for sexual relationships, sexual orientation, handedness and sibling SR. Lesbian embryos could induce tolerance from mothers with anti-female factors. Non-right-handedness could induce maternal tolerance, or change the maternal compatibility of "gay" embryos. Alternatively, gay embryos could be poor inducers of maternal tolerance towards male traits. |
| | |
Authors:
|
Carlos Y Valenzuela |
Related Documents
:
|
1365697 - Relationship of first-trimester subchorionic bleeding detected by color doppler ultraso... 10492867 - Feasibility of the second-trimester fetal ultrasound examination in an unselected popul... 16275217 - Structural and functional early human development assessed by three-dimensional and fou... 3585877 - Antenatal detection of hypoplastic right ventricle with fetal m-mode echocardiography. ... 15507967 - Polymorphisms in the tumor necrosis factor-alpha gene at position -308 and the inducibl... 15970647 - Specific measurement of o-linked core 2 sugar-containing isoforms of hyperglycosylated ... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2010-11-30 |
Journal Detail:
|
Title: Biological research Volume: 43 ISSN: 0717-6287 ISO Abbreviation: - Publication Date: 2010 00 |
Date Detail:
|
Created Date: 2011-1-20 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9308271 Medline TA: Biol Res Country: - |
Other Details:
|
Languages: ENG Pagination: 347-356 Citation Subset: - |
Affiliation:
|
Programa de Genética Humana, ICBM, Facultad de Medicina, Universidad de Chile, Santiago, Chile. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Histocompatibility and Immunogenetics in Cord Blood Transplantation.
Next Document: Chronic toxicity bioassay with populations of the crustacean Artemia salina exposed to the organopho...