Document Detail


Sexual dimorphism in campylobacteriosis.
MedLine Citation:
PMID:  18062834     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sexual dimorphism in infectious diseases whereby disease incidence is more prevalent in one gender has been reported repeatedly in the scientific literature. Both behavioural and physiological differences have been suggested as a cause of this gender bias but there is a paucity of data to support either of these viewpoints. Here it is hypothesized that for campylobacteriosis physiological factors play an important role in the higher incidence in males. We demonstrate in the human population (from several countries in three continents) that this bias exists in young children (<1 year) where behavioural differences between genders are likely to be minimal. Further we demonstrate this difference in an animal model where both infection rates and shedding rates of the organism are greater in male mice.
Authors:
N J C Strachan; R O Watson; V Novik; D Hofreuter; I D Ogden; J E Galán
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-12-07
Journal Detail:
Title:  Epidemiology and infection     Volume:  136     ISSN:  0950-2688     ISO Abbreviation:  Epidemiol. Infect.     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-10-07     Completed Date:  2008-11-18     Revised Date:  2013-06-06    
Medline Journal Info:
Nlm Unique ID:  8703737     Medline TA:  Epidemiol Infect     Country:  England    
Other Details:
Languages:  eng     Pagination:  1492-5     Citation Subset:  IM    
Affiliation:
School of Biological Sciences, University of Aberdeen, Cruickshank Building, Aberdeen, UK. n.strachan@abdn.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Animals
Campylobacter Infections / epidemiology*
Child
Child, Preschool
Colony Count, Microbial
Feces / microbiology
Female
Humans
Incidence
Infant
Infant, Newborn
Male
Mice
Middle Aged
Sex Factors
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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