Document Detail


Sexual dimorphism in amino acid compositions of mouse prolactin.
MedLine Citation:
PMID:  4026864     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sexual dimorphism was found in amino acid compositions and immunogenecity of variant types of prolactin (PRL) purified from the pituitary gland of normal adult C57BL mice by a high performance liquid chromatography. From the pituitary gland of female mice, three female variant types of PRL were isolated, whereas from the pituitary gland of male mice, two male variant types of PRL (M1-PRL and M3-PRL) and a female variant type of PRL (M2-PRL) were obtained. The amino acid composition of M3-PRL was different from any of female variant types which were very similar to each other and contained less varine, isoleucine, leucine, tyrosine and lysine but more alanine than the latter. Immunoreactivity of any of female variant types of PRL against anti-PRL serum was 100%, whereas that of M1-PRL was as much as 85% and that of M3-PRL was nearly undetectable.
Authors:
H Hashimoto; T Yasuhara; T Nakajima; T Harigaya; K Hoshino
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biochemical and biophysical research communications     Volume:  130     ISSN:  0006-291X     ISO Abbreviation:  Biochem. Biophys. Res. Commun.     Publication Date:  1985 Aug 
Date Detail:
Created Date:  1985-09-25     Completed Date:  1985-09-25     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0372516     Medline TA:  Biochem Biophys Res Commun     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1209-16     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Amino Acids / analysis
Animals
Chromatography, Gel
Chromatography, High Pressure Liquid
Female
Genetic Variation
Male
Mice
Pituitary Gland / analysis*
Prolactin / genetics*,  isolation & purification
Sex Factors
Chemical
Reg. No./Substance:
0/Amino Acids; 9002-62-4/Prolactin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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