Document Detail


Sex steroids, pregnancy-associated hormones and immunity to parasitic infection.
MedLine Citation:
PMID:  15275288     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
A wealth of evidence has accumulated that illustrates the ability of sex-associated hormones to influence directly a variety of diverse immunological functions. Thus, it is not surprising that differences have also been noted between the sexes in their relative susceptibility to parasitic infections. Furthermore, during pregnancy, much of the observed maternal immunomodulation, essential for fetal survival, has been attributed to changes in the levels of steroid hormones. These pregnancy-induced alterations in immune function can also have profound effects on the course of parasitic infection. In this article, Craig Roberts, Abhay Satoskar and James Alexander review the immunological basis for differences in the relative susceptibilities of males, non-pregnant females and pregnant females to parasitic infection, particularly leislumaniasis and toxoplasmosis. They also discuss the role of the major sex- and pregnancy-associated hormones in mediating these effects.
Authors:
C W Roberts; A Satoskar; J Alexander
Related Documents :
17293908 - Hiv-1 viremia during the first 28 weeks of pregnancy is not associated with mother-to-c...
16181268 - Ocular toxoplasmosis in pregnancy.
17336588 - Perinatal group b streptococcal disease.
9252888 - Urinary tract infection during pregnancy: a risk factor for cerebral palsy?
3625588 - The relationship between expectations of pregnancy and birth, and transient depression ...
17489508 - What do young adults expect when they go online? lessons for development of an std/hiv ...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Parasitology today (Personal ed.)     Volume:  12     ISSN:  0169-4758     ISO Abbreviation:  Parasitol. Today (Regul. Ed.)     Publication Date:  1996 Oct 
Date Detail:
Created Date:  2004-07-27     Completed Date:  2005-04-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8605563     Medline TA:  Parasitol Today     Country:  England    
Other Details:
Languages:  eng     Pagination:  382-8     Citation Subset:  -    
Affiliation:
Division of Infectious Diseases, Michael Reese Hospital and Medical Center, 2929 South Ellis Avenue, Chicago, IL 60616-3390, USA. C.Roberts@UIC.EDU
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Models for malaria: Nature knows best.
Next Document:  Tick salivary prostaglandins: Presence, origin and significance.