Document Detail

Sex steroid receptors in papilloma, normal mucosa and polyps of the nose.
MedLine Citation:
PMID:  8202314     Owner:  NLM     Status:  MEDLINE    
Sex steroid hormone receptors (SSHR) were determined in 14 cases of sinonasal papillomas, 17 cases of nasal polyps and in the normal nasal mucosa of 13 patients. The determination of SSHR was done by the dextran-coated charcoal assay from cytosol protein. All the cases of sinonasal papilloma were SSHR negative, while some specimens of normal nasal mucosa contained small amounts of SSHR. In addition, some cases of nasal polyps were found to contain low concentrations of the receptors, but concentrations were lower than those found in normal mucosa. Although nasal papillomas are more common in men than in women, this study shows that SSHR do not play any role in the development of these tumors.
L Siivonen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  ORL; journal for oto-rhino-laryngology and its related specialties     Volume:  56     ISSN:  0301-1569     ISO Abbreviation:  ORL J. Otorhinolaryngol. Relat. Spec.     Publication Date:    1994 May-Jun
Date Detail:
Created Date:  1994-07-07     Completed Date:  1994-07-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0334721     Medline TA:  ORL J Otorhinolaryngol Relat Spec     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  154-6     Citation Subset:  IM    
Department of Otorhinolaryngology, University of Turku, Finland.
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MeSH Terms
Ethmoid Sinus / chemistry
Maxillary Sinus Neoplasms / chemistry
Middle Aged
Nasal Mucosa / chemistry*
Nasal Polyps / chemistry*
Nose Neoplasms / chemistry*
Papilloma / chemistry*
Paranasal Sinus Neoplasms / chemistry
Receptors, Androgen / analysis*
Receptors, Estrogen / analysis*
Receptors, Progesterone / analysis*
Reg. No./Substance:
0/Receptors, Androgen; 0/Receptors, Estrogen; 0/Receptors, Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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