Document Detail


Sex differences in substrate oxidation during aerobic exercise in obese men and postmenopausal obese women.
MedLine Citation:
PMID:  19501865     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study was to compare substrate oxidation during aerobic exercise in obese men and postmenopausal obese women. Ten obese men (mean age, 55.4 +/- 2.2 years; body mass index, 27.5 +/- 0.4 kg/m(2); peak oxygen uptake [Vo(2)peak], 44.4 +/- 1.9 mL/kg fat-free mass/min; mean +/- SE] and 10 postmenopausal obese women (mean age, 57.2 +/- 1.2 years; body mass index, 27.9 +/- 0.5 kg/m(2); VO(2)peak, 39.9 +/- 1.3 mL/kg fat-free mass/min) performed a 40-minute bout of cycling exercise at 50% VO(2)peak. Blood samples were collected for assessment of metabolic variables and 17beta-estradiol concentration at baseline and during aerobic exercise. Breath samples were collected to estimate carbohydrate and fat oxidation using a digital computer-based breath-by-breath exercise analysis system during aerobic exercise. Serum 17beta-estradiol concentration was not significantly different between the men and women subjects at baseline (P > .05). Serum free fatty acid concentration tended to be higher in the men than in the women (P = .07) during the exercise, but the respiratory exchange ratio during exercise was lower in women than in men (P < .05). Fat oxidation adjusted for fat-free mass was higher (P < .05) in women than in men. These results suggest that fat utilization was higher during aerobic exercise in postmenopausal obese women than in obese men and did not depend on resting serum 17beta-estradiol concentration.
Authors:
Shigeharu Numao; Yoichi Hayashi; Yasutomi Katayama; Tomoaki Matsuo; Kiyoji Tanaka
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-06-18
Journal Detail:
Title:  Metabolism: clinical and experimental     Volume:  58     ISSN:  1532-8600     ISO Abbreviation:  Metab. Clin. Exp.     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-08-18     Completed Date:  2009-09-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375267     Medline TA:  Metabolism     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1312-9     Citation Subset:  IM    
Affiliation:
Faculty of Sport Sciences, Waseda University, Tokorozawa, Saitama 359-1192, Japan. numashige@aoni.waseda.jp
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MeSH Terms
Descriptor/Qualifier:
Epinephrine / blood
Estradiol / blood
Exercise / physiology*
Female
Heart Rate / physiology
Humans
Male
Middle Aged
Norepinephrine / blood
Obesity / blood,  metabolism*,  physiopathology
Oxidation-Reduction*
Postmenopause / metabolism*,  physiology
Respiratory Function Tests
Sex Characteristics*
Chemical
Reg. No./Substance:
50-28-2/Estradiol; 51-41-2/Norepinephrine; 51-43-4/Epinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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