Document Detail

Sex differences in pulmonary function during exercise.
MedLine Citation:
PMID:  18317379     Owner:  NLM     Status:  MEDLINE    
Structural and hormonal sex differences are known to exist that may influence the pulmonary system's response to exercise. Specifically, women tend to show reduced lung size, decreased maximal expiratory flow rates, reduced airway diameter, and a smaller diffusion surface than age- and height-matched men. Additionally, ovarian hormones, namely progesterone and estrogen, are known to modify and influence the pulmonary system. These differences may have an effect on airway responsiveness, ventilation, respiratory muscle work, and pulmonary gas exchange during exercise. Recent evidence suggests that during exercise, women demonstrate greater airway hyperresponsiveness and expiratory flow limitation, increased work of breathing, and, perhaps, greater exercise-induced arterial hypoxemia compared with men. The consequence of these pulmonary effects may influence exercise capacity.
Craig A Harms; Sara Rosenkranz
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Medicine and science in sports and exercise     Volume:  40     ISSN:  0195-9131     ISO Abbreviation:  Med Sci Sports Exerc     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-03-18     Completed Date:  2008-06-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8005433     Medline TA:  Med Sci Sports Exerc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  664-8     Citation Subset:  IM; S    
Department of Kinesiology, Kansas State University, Manhattan, KS 66506, USA.
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MeSH Terms
Adaptation, Physiological*
Airway Resistance
Anoxia / etiology,  physiopathology
Exercise / physiology*
Gonadal Steroid Hormones / physiology*
Motor Activity*
Pulmonary Gas Exchange / physiology*
Sex Factors
Reg. No./Substance:
0/Gonadal Steroid Hormones

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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