Document Detail


Sex differences in antidepressant-like effect of chronic repetitive transcranial magnetic stimulation in rats.
MedLine Citation:
PMID:  17291659     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neurophysiological technique. Pre-clinical and clinical studies supported that rTMS might have antidepressant effects. However, whether antidepressant effect of chronic rTMS is gender-dependent is still unknown. In this study, male and female Wistar rats received 10-day rTMS (4 trains of 15 Hz; 200 stimuli/day; 1.0 T) or control condition, and then were subjected to the forced-swim test (FST). We found that female rats consistently showed higher activity levels than males in FST and revealed the significant effects of gender and rTMS as well as the interaction of gender and rTMS. The result suggested the antidepressant-like effects of chronic rTMS on behavioral components in FST are gender-dependent. The gender discrepancy related to rTMS should not be neglected in antidepressant treatment of rTMS.
Authors:
Yuye Yang; Wei Li; Bin Zhu; Yanyou Liu; Bo Yang; Hongxing Wang; Zhengrong Wang
Related Documents :
2436249 - Effect of lithium administration on rat brain 5-hydroxyindole levels in a possible anim...
16846729 - Effect of lithium carbonate on subchondral bone in sexually mature wistar rats.
18358519 - Confirmation of antidepressant potential of the selective beta3 adrenoceptor agonist am...
3020329 - Aluminum increases cyclic amp in rat cerebral cortex in vivo.
978569 - Lithium protection against oxygen toxicity in rats: ammonia and amino acid metabolism.
11785909 - Effect of glucocorticoid dexamethasone on cyclic amp formation stimulated by pituitary ...
12199529 - Unaltered caffeine-induced relaxation in the aorta of stroke-prone spontaneously hypert...
15925749 - Chronic administration of resveratrol prevents biochemical cardiovascular changes in fr...
11744219 - Protective effect of insulin-like-growth-factor-1 against dopamine-induced neurotoxicit...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-01-16
Journal Detail:
Title:  Progress in neuro-psychopharmacology & biological psychiatry     Volume:  31     ISSN:  0278-5846     ISO Abbreviation:  Prog. Neuropsychopharmacol. Biol. Psychiatry     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-03-30     Completed Date:  2007-06-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8211617     Medline TA:  Prog Neuropsychopharmacol Biol Psychiatry     Country:  England    
Other Details:
Languages:  eng     Pagination:  735-40     Citation Subset:  IM    
Affiliation:
Laboratory of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, 610041 Sichuan, People's Republic of China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Analysis of Variance
Animals
Behavior, Animal / physiology*,  radiation effects
Brain / radiation effects
Female
Immobility Response, Tonic / physiology,  radiation effects
Male
Motor Activity / physiology,  radiation effects
Rats
Rats, Wistar
Reaction Time / physiology,  radiation effects
Sex Characteristics*
Swimming / psychology
Transcranial Magnetic Stimulation*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Meta-analysis of the association of serotonin transporter gene polymorphism with obsessive-compulsiv...
Next Document:  Association study of serotonin 2A receptor (5-HT2A) and serotonin transporter (5-HTT) gene polymorph...