Document Detail

Sex and age differences in pulmonary mechanics in normal nonsmoking subjects.
MedLine Citation:
PMID:  972127     Owner:  NLM     Status:  MEDLINE    
Maximun flow-volume, static pressure-volume, and maximum flow static recoil curves of three groups of nonsmoking, normal subjects (young men, young women, elderly women) were used to assess age and sex differences in pulmonary mechanics. No significant sex differences in maximum flow were seen but the young men showed higher lung recoil pressures at full inflation. When the influence of the inspiratory muscles and chest wall was excluded by exponential extrapolation of the pressure-volume curves to a maximum volume the bulk elastic properties of the lungs of young men and women appeared identical. Loss of maximum expiratory flow at low lung volumes and of lung recoil pressure occurred with age in nonsmoking women in whom emphysema should be minimal and therefore indicate true physiological effects of aging. The changes in pulmonary mechanics with age are consistent with an increase in unstressed dimensions and loss of elastic recoil of both alveoli and airways.
G J Gibson; N B Pride; C O'cain; R Quagliato
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of applied physiology     Volume:  41     ISSN:  0021-8987     ISO Abbreviation:  J Appl Physiol     Publication Date:  1976 Jul 
Date Detail:
Created Date:  1976-12-03     Completed Date:  1976-12-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376576     Medline TA:  J Appl Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  20-5     Citation Subset:  IM    
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MeSH Terms
Age Factors
Lung / physiology*
Lung Compliance
Middle Aged
Pulmonary Ventilation
Sex Factors
Ventilation-Perfusion Ratio
Vital Capacity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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