Document Detail

Sex peptide is required for the efficient release of stored sperm in mated Drosophila females.
MedLine Citation:
PMID:  20679516     Owner:  NLM     Status:  MEDLINE    
The Drosophila seminal fluid protein (SFP) sex peptide (SP) elicits numerous post-mating responses, including increased egg laying and decreased sexual receptivity, in the mated female. Unlike other SFPs, which are detectable in mated females for only a few hours post mating, SP is maintained-and its effects are sustained-for several days. The persistence of SP in the mated female's reproductive tract is thought to be a consequence of its binding to, and gradual release from, sperm in storage, which maintains SP's ability to act within the female reproductive tract. Recent studies have shown that several other SFPs, acting in a network, are needed for SP's localization to sperm and are necessary for the efficient release of sperm from storage. This result suggested an additional new role for SP modulating the release of sperm from storage. We tested for this possibility by examining sperm storage parameters in mated females that did not receive SP. We found that while sperm accumulation into storage was unaffected, sperm depletion from storage sites was significantly decreased (or impaired) in the absence of SP. Mates of males expressing a modified SP that is unable to be released from sperm showed a similar phenotype, indicating that release of sperm-bound SP is a necessary component of normal sperm depletion. Additionally, SP null males were more successful in a sperm competitive environment when they were first to mate, which is likely a consequence of higher retention of their sperm due to defective sperm release. Our findings illustrate a direct role for SP in the release of sperm from storage.
Frank W Avila; K Ravi Ram; Margaret C Bloch Qazi; Mariana F Wolfner
Related Documents :
23926746 - The effect of powder:liquid ratio and pre-mixing on sealing properties of roth 801 sealer.
7106316 - The effect of albumin gradients and human serum on the longevity and fertilizing capaci...
1349186 - Sperm size and sperm competition in birds.
11329806 - A sperm cell toxicity test procedure for the mediterranean species paracentrotus lividu...
19644966 - Shape, height, and location of the lingula for sagittal ramus osteotomy in thais.
15264326 - Influence of cross-linked pmma beads on the mechanical behavior of self-curing acrylic ...
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2010-08-02
Journal Detail:
Title:  Genetics     Volume:  186     ISSN:  1943-2631     ISO Abbreviation:  Genetics     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-10-13     Completed Date:  2011-03-21     Revised Date:  2014-09-17    
Medline Journal Info:
Nlm Unique ID:  0374636     Medline TA:  Genetics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  595-600     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Drosophila Proteins / genetics,  physiology*
Drosophila melanogaster / genetics,  physiology*
Peptides / genetics,  physiology*
Semen / physiology*
Spermatozoa / physiology*
Grant Support
Reg. No./Substance:
0/Drosophila Proteins; 0/Peptides

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Promoter strength influences the S phase requirement for establishment of silencing at the Saccharom...
Next Document:  Genomic admixture analysis in European Populus spp. reveals unexpected patterns of reproductive isol...