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Sevoflurane versus propofol anesthesia in patients undergoing lumbar spondylodesis: a randomized trial.
MedLine Citation:
PMID:  23073511     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Spondylodesis is a procedure aiming at providing stability in one or more spinal segments. The aim of our study was to compare sevoflurane and propofol as induction and maintenance agents, focusing on hemodynamic stability, recovery characteristics, postoperative nausea and vomiting, and pain intensity. MATERIALS AND METHODS: Seventy patients, with a physical status according to American Society of Anesthesiologists (ASA) I-II, 50-72 y old, undergoing selective lumbar spondylodesis were enrolled. RESULTS: There was no statistically significant difference between groups in overall mean hemodynamic parameters. No differences in fluid administration and vasoactive substances used were noted. Postoperatively, there was a significant difference in overall mean visual analog score at rest and at cough, with the sevoflurane group showing lower values. No differences in the incidence of nausea, vomiting, shivering, postoperative sedation scores, and orientation to place were revealed. Orientation to time exhibited a statistically significant difference at the time just after transfer to the post-anesthesia care unit, where more patients of the sevoflurane group seemed to be well oriented. CONCLUSIONS: Sevoflurane and propofol anesthesia for lumbar spondylodesis surgery provide safe and comparable results.
Authors:
Konstantinos Konstantopoulos; Alexandros Makris; Alexandra Moustaka; Iosifina Karmaniolou; Georgios Konstantopoulos; Argyro Mela
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-10
Journal Detail:
Title:  The Journal of surgical research     Volume:  -     ISSN:  1095-8673     ISO Abbreviation:  J. Surg. Res.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376340     Medline TA:  J Surg Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Affiliation:
Department of Anaesthesiology, Asklepieion Hospital, Athens, Greece.
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