Document Detail

Sevoflurane increases glucose transport in skeletal muscle cells.
MedLine Citation:
PMID:  12088955     Owner:  NLM     Status:  MEDLINE    
IMPLICATIONS: Sevoflurane anesthesia has an inhibitory effect on insulin secretion. Glucose concentrations in plasma do not significantly change during sevoflurane anesthesia. Plasma glucose concentrations are affected by intracellular glucose metabolism. However, glucose transport into cells during sevoflurane anesthesia remains unclear.
Akira Kudoh; Hiroshi Katagai; Tomoko Takazawa
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Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  95     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:  2002 Jul 
Date Detail:
Created Date:  2002-06-28     Completed Date:  2002-07-23     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  123-8, table of contents     Citation Subset:  AIM; IM    
Department of Anesthesiology, University of Hirosaki School of Medicine, Hirosaki National Hospital, 1 Tominocho, Hirosaki 036-8545, Aomori, Japan.
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MeSH Terms
Anesthetics, Inhalation / pharmacology*
Antimetabolites / metabolism
Biological Transport, Active / drug effects
Calcium / metabolism
Cell Separation
Deoxyglucose / metabolism
Enzyme Activation / drug effects
Enzyme Inhibitors / pharmacology
Glucose / metabolism*
Methyl Ethers / pharmacology*
Muscle, Skeletal / cytology,  drug effects,  metabolism*
Phosphatidylinositol 3-Kinases / antagonists & inhibitors,  metabolism
Protein Kinase C / antagonists & inhibitors,  metabolism
Protein-Tyrosine Kinases / antagonists & inhibitors,  metabolism
Reg. No./Substance:
0/Anesthetics, Inhalation; 0/Antimetabolites; 0/Enzyme Inhibitors; 0/Methyl Ethers; 154-17-6/Deoxyglucose; 28523-86-6/sevoflurane; 50-99-7/Glucose; 7440-70-2/Calcium; EC 2.7.1.-/Phosphatidylinositol 3-Kinases; EC Kinases; EC Kinase C

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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