Document Detail


Sevoflurane anesthesia in desert tortoises (Gopherus agassizii).
MedLine Citation:
PMID:  10367645     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effects of sevoflurane on anesthesia induction, recovery, ventricular pressures, heart rate, ventricular pH, blood gas values, and electrolytes were evaluated in desert tortoises (Gopherus agassizii). Tortoises were orotracheally intubated while awake and ventilated manually with 3-7% sevoflurane in oxygen (1 L/min) to achieve desired expired sevoflurane concentrations. Data, consisting of induction time, recovery time, systolic, diastolic, and mean ventricular pressures, heart rate, ventricular pH, blood gas values, and electrolytes, were collected prior to anesthesia and sequentially at 2.50% and 3.75% expired sevoflurane as measured at the junction of the endotracheal tube and the breathing circuit. Blood pressure was measured and blood samples were collected through a 25-ga needle passed through a cardiac access port that was placed while the tortoises were in dorsal recumbency. Mean (+/-SE) induction time was 2.55+/-0.55 min, recovery time was 27.58+/-7.55 min, and duration of anesthesia was 105+/-12 min. Mean (+/-SD) values for systolic, diastolic, and mean ventricular pressures in awake tortoises were 28+/-3 mm Hg, 22+/-2 mm Hg, and 24+/-2 mm Hg, respectively. Sevoflurane (2.5% expired) significantly decreased systolic (14+/-3 mm Hg), diastolic (12+/-1 mm Hg), and mean (13+/-1 mm Hg) ventricular pressures compared with those of awake tortoises. Ventricular pressures did not decrease further with increasing depth of anesthesia. Heart rate (32+/-4 beats/min) did not change significantly under sevoflurane anesthesia. Sevoflurane administration increased ventricular PO2 but did not change Na+, K+, or iCa++ concentrations. Sevoflurane appears to provide safe and effective anesthesia with rapid induction and recovery.
Authors:
M B Rooney; G Levine; J Gaynor; E Macdonald; J Wimsatt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians     Volume:  30     ISSN:  1042-7260     ISO Abbreviation:  J. Zoo Wildl. Med.     Publication Date:  1999 Mar 
Date Detail:
Created Date:  1999-11-22     Completed Date:  1999-11-22     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  8915208     Medline TA:  J Zoo Wildl Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  64-9     Citation Subset:  IM    
Affiliation:
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523, USA.
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MeSH Terms
Descriptor/Qualifier:
Anesthetics, Inhalation* / pharmacology
Animals
Blood Gas Analysis / veterinary
Carbon Dioxide / blood
Electrolytes / blood
Female
Heart Rate / drug effects
Hydrogen-Ion Concentration
Male
Methyl Ethers* / pharmacology
Oxygen / blood
Turtles / physiology*
Ventricular Pressure / drug effects*
Chemical
Reg. No./Substance:
0/Anesthetics, Inhalation; 0/Electrolytes; 0/Methyl Ethers; 124-38-9/Carbon Dioxide; 28523-86-6/sevoflurane; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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