| Severity of episcleritis and systemic disease association. | |
| | |
MedLine Citation:
|
PMID: 10201593 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To analyze patient characteristics and correlate between the site and severity of the inflammation and ocular and/or systemic disease association in a cohort of patients with episcleritis. DESIGN: Retrospective case series. METHODS: Medical records of 100 patients with episcleritis were reviewed. Data were analyzed using a customized database software. RESULTS: The age range at presentation was 18 to 76 years (mean, 43; median, 44). Sixty-nine percent of the patients were female. Thirty-two (32%) patients had bilateral involvement. The episcleritis was nodular in 23 eyes (16%). Half of the patients had a concurrent eye disease. Associated systemic disease was found in 36 patients (36%). In two patients, episcleritis preceded a systemic vasculitic disease (Wegener granulomatosis and Cogan syndrome). Ocular complications included uveitis (11.4%), corneal involvement (15%), and glaucoma (7.8%). No significant correlation of the site and severity of inflammation to the presence of associated systemic or ocular diseases was found. The mean follow-up was 16.5 months. Twenty-eight patients experienced recurrence of episcleritis during the follow-up. Half of the patients required treatment with oral nonsteroidal anti-inflammatory drugs. CONCLUSIONS: Episcleritis is usually a benign, self-limited disease, but it should not be trivialized since it may be associated with systemic disease and ocular complications. A careful review of systems should be performed in all patients presenting with episcleritis, and this should be repeated at least annually during the follow-up. A thorough eye examination is obviously essential to detect and treat ocular complications. |
| | |
Authors:
|
E K Akpek; H S Uy; W Christen; C Gurdal; C S Foster |
Related Documents
:
|
10671333 - A prospective search for ocular lesions in hospitalized patients with significant bacte... 17651463 - Pattern of ocular manifestations in patients with sarcoidosis in developing countries. 3113713 - Acute gangrene of the scrotum and penis in four hematologic patients. the usefulness of... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Ophthalmology Volume: 106 ISSN: 0161-6420 ISO Abbreviation: Ophthalmology Publication Date: 1999 Apr |
Date Detail:
|
Created Date: 1999-04-15 Completed Date: 1999-04-15 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 7802443 Medline TA: Ophthalmology Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 729-31 Citation Subset: IM |
Affiliation:
|
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston 02114, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Anti-Inflammatory Agents, Non-Steroidal / therapeutic use Cohort Studies Eye Diseases / complications Female Glucocorticoids / therapeutic use Humans Male Middle Aged Recurrence Retrospective Studies Scleritis / complications*, drug therapy, physiopathology Severity of Illness Index Vasculitis / complications*, drug therapy, physiopathology |
| Chemical | |
Reg. No./Substance:
|
0/Anti-Inflammatory Agents, Non-Steroidal; 0/Glucocorticoids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Tacrolimus (FK506) in the treatment of posterior uveitis refractory to cyclosporine.
Next Document: Prospective randomized comparison of simultaneous and sequential bilateral laser in situ keratomileu...