| Severe type III hyperlipoproteinemia in two patients maintained on chronic hemodialysis. | |
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MedLine Citation:
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PMID: 2319734 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two patients with severe hyperlipidemia receiving long-term hemodialysis were classified as type III hyperlipoproteinemic subjects. They are homozygous for apolipoprotein E2 and have an elevated VLDL-cholesterol/plasma-triglyceride ratio. The dyslipoproteinemia was severely aggravated by the renal failure, but careful treatment with bezafibrate was able to effectively lower elevated serum lipids. Accurate diagnosis of lipid abnormalities in patients with chronic renal failure seems to be necessary to plan appropriate therapeutic interventions and to lower the risk for accelerated atherosclerosis. |
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Authors:
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G Feussner; J Bommer; R Ziegler |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Klinische Wochenschrift Volume: 68 ISSN: 0023-2173 ISO Abbreviation: Klin. Wochenschr. Publication Date: 1990 Jan |
Date Detail:
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Created Date: 1990-05-03 Completed Date: 1990-05-03 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 2985205R Medline TA: Klin Wochenschr Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 65-70 Citation Subset: IM |
Affiliation:
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Medizinische Klinik der Universität Heidelberg, Abteilung Innere Medizin I. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Apolipoproteins E
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blood,
genetics Arteriosclerosis / blood* Bezafibrate / administration & dosage Cholesterol / blood Female Heterozygote Detection Humans Hyperlipoproteinemia Type III / blood*, drug therapy, genetics Kidney Failure, Chronic / blood* Kidney Function Tests Lipids / blood* Lipoproteins / blood Middle Aged Renal Dialysis* Risk Factors Triglycerides / blood |
| Chemical | |
Reg. No./Substance:
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0/Apolipoproteins E; 0/Lipids; 0/Lipoproteins; 0/Triglycerides; 41859-67-0/Bezafibrate; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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