| Severe systemic autoimmune disease associated with Epstein-Barr virus infection. | |
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MedLine Citation:
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PMID: 15591906 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Infection with Epstein-Barr virus (EBV) has been associated with different autoimmune manifestations. The authors describe a girl who developed a severe systemic autoimmune disease with severe autoimmune hemolytic anemia, mild autoimmune thrombopenia, antineutrophil antibodies, and fatal autoimmune hepatitis after EBV infection. Despite immunosuppressive treatment and ultimately liver transplantation, this patient could not overcome her clinical condition and died. The etiopathogenesis of this complex disease and the association with EBV infection is discussed. |
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Authors:
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Julián Sevilla; Maria del Carmen Escudero; Raquel Jiménez; Marta González-Vicent; Javier Manzanares; Dolores García-Novo; Luis Madero |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of pediatric hematology/oncology Volume: 26 ISSN: 1077-4114 ISO Abbreviation: J. Pediatr. Hematol. Oncol. Publication Date: 2004 Dec |
Date Detail:
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Created Date: 2004-12-13 Completed Date: 2005-01-21 Revised Date: 2011-10-06 |
Medline Journal Info:
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Nlm Unique ID: 9505928 Medline TA: J Pediatr Hematol Oncol Country: United States |
Other Details:
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Languages: eng Pagination: 831-3 Citation Subset: IM |
Affiliation:
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Pediatric Oncohematology, Hospital Niño Jesús, Menéndez Pelayo 65, Madrid 28009, Spain. jsevilla.hnjs@salud.madrid.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anemia, Hemolytic
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etiology*,
immunology,
pathology Antibodies, Antinuclear Autoimmune Diseases / etiology*, pathology Epstein-Barr Virus Infections / complications* Fatal Outcome Female Hepatitis / etiology*, immunology*, pathology Humans Immunosuppressive Agents / therapeutic use Infant Liver Transplantation Thrombocytopenia / etiology |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Antinuclear; 0/Immunosuppressive Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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