Document Detail


Severe slowly resolving heroin-induced pulmonary edema.
MedLine Citation:
PMID:  798658     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Severe heroin-induced pulmonary edema occurred in three previously healthy young men. Adequate arterial PO2 could only be achieved with the use of positive endexpiratory pressure (PEEP). Recovery was characterized by the gradual clearing of the pulmonary infiltrates and a gradual lessening of the severe restrictive ventilatory defects over many weeks. Concomitant aspiration of gastric acid was thought to be the explanation for the severity of these cases. In cases such as these, initial vigorous therapy, including PEEP for hypoxia, corticosteroids for possible aspiration and volume replacement for hypotension, is recommended.
Authors:
R W Light; T R Dunham
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Chest     Volume:  67     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1975 Jan 
Date Detail:
Created Date:  1977-05-25     Completed Date:  1977-05-25     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  61-4     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adrenal Cortex Hormones / therapeutic use
Adult
Anoxia / drug therapy,  etiology,  therapy
Gastric Juice
Heroin / adverse effects*
Humans
Hypotension / etiology
Inhalation
Male
Positive-Pressure Respiration
Pulmonary Edema / chemically induced*,  complications,  drug therapy
Vital Capacity
Chemical
Reg. No./Substance:
0/Adrenal Cortex Hormones; 561-27-3/Heroin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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