Document Detail

Severe "silent" mitral regurgitation. A potentially reversible cause of refractory heart failure.
MedLine Citation:
PMID:  2752805     Owner:  NLM     Status:  MEDLINE    
Hemodynamically critical ("severe") mitral regurgitation is usually associated with an audible (if not loud) systolic murmur and signs of left ventricular volume overload. However, "silent" severe mitral regurgitation is being increasingly recognized. We review the case histories of nine patients with silent hemodynamically important mitral regurgitation (associated with acute myocardial infarction and chronic valvular, hypertrophic, and ischemic heart disease), six of whom survived mitral valve replacement, of whom five are alive and functioning well more than three years postoperatively. Performance of left ventriculography early in the hospital course of patients with severe unexplained congestive heart failure (with normal or near-normal left ventricular systolic function assessed noninvasively) identifies patients with severe silent mitral regurgitation who may have long-term benefit from mechanical therapy.
T L Schreiber; J Fisher; A Mangla; D Miller
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Chest     Volume:  96     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1989 Aug 
Date Detail:
Created Date:  1989-09-01     Completed Date:  1989-09-01     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  242-6     Citation Subset:  AIM; IM    
Division of Cardiology, New York Hospital-Cornell Medical Center, New York.
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MeSH Terms
Heart Auscultation*
Heart Catheterization
Heart Failure / etiology*
Heart Murmurs*
Heart Valve Prosthesis
Middle Aged
Mitral Valve
Mitral Valve Insufficiency / complications*,  diagnosis,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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