| Severe sepsis in cats: 29 cases (1986-1998). | |
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MedLine Citation:
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PMID: 10953718 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To document the clinical, clinicopathologic, and pathologic findings in cats with severe sepsis, identify abnormalities unique to this species, and identify criteria that could be used antemortem to diagnose the systemic inflammatory response syndrome in cats. DESIGN: Retrospective study. ANIMALS: 29 cats confirmed to have severe sepsis at necropsy. PROCEDURE: Pertinent history, physical examination findings, and results of hematologic and biochemical testing were extracted from medical records. RESULTS: Clinical diagnoses included pyothorax, septic peritonitis, bacteremia secondary to gastrointestinal tract disease, pneumonia, endocarditis, pyelonephritis, osteomyelitis, pyometra, and bite wounds. Physical examination findings included lethargy, pale mucous membranes, poor pulse quality, tachypnea, hypo- or hyperthermia, signs of diffuse pain on abdominal palpation, bradycardia, and icterus. Clinicopathologic abnormalities included anemia, thrombocytopenia, band neutrophilia, hypoalbuminemia, low serum alkaline phosphatase activity, and hyperbilirubinemia. Necropsy findings included multi-organ necrosis or inflammation with intralesional bacteria. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that severe sepsis in cats is characterized by lethargy, pale mucous membranes, signs of diffuse abdominal pain, tachypnea, bradycardia, weak pulses, anemia, hypoalbuminemia, hypothermia, and icterus. Recognition of this combination of clinical findings should facilitate the diagnosis of severe sepsis in cats. |
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Authors:
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C A Brady; C M Otto; T J Van Winkle; L G King |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the American Veterinary Medical Association Volume: 217 ISSN: 0003-1488 ISO Abbreviation: J. Am. Vet. Med. Assoc. Publication Date: 2000 Aug |
Date Detail:
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Created Date: 2000-10-05 Completed Date: 2001-09-06 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7503067 Medline TA: J Am Vet Med Assoc Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 531-5 Citation Subset: IM |
Affiliation:
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Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Autopsy / veterinary Blood Chemical Analysis / veterinary Cat Diseases / blood, diagnosis*, pathology Cats Female Hematologic Tests / veterinary Inflammation / veterinary Male Necrosis Retrospective Studies Sepsis / diagnosis, pathology, veterinary* Systemic Inflammatory Response Syndrome / diagnosis, pathology, veterinary |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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