| Severe recurrent hypoglycaemia following discontinuation of olanzapine. | |
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MedLine Citation:
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PMID: 21573263 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Severe hypoglycaemia is a diagnostic challenge.1 It is often explained by mismatch between insulin doses, food ingestion and exercise. Recurrent hypoglycaemia can indicate underlying medical problems. Drug related events usually concern insulin or sulphonylureas. However, withdrawal of drugs which can cause insulin resistance can be causative if insulin or sulphonylureas continue.2We report the case of an insulin-treated patient who presented with severe recurrent hypoglycaemia. After exclusion of secondary causes of hypoglycaemia it was established that at the time of diagnosis of diabetes he had been taking olanzapine. This had subsequently been discontinued. Olanzapine is recognised to cause diabetes and diabetic ketoacidosis. Our patient was able to discontinue insulin therapy. |
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Authors:
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Sarah Steven; Rahul Nayar |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acute medicine Volume: 10 ISSN: 1747-4884 ISO Abbreviation: Acute Med Publication Date: 2011 |
Date Detail:
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Created Date: 2011-05-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101553725 Medline TA: Acute Med Country: England |
Other Details:
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Languages: eng Pagination: 32-4 Citation Subset: IM |
Affiliation:
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MBChB BSc (Hons) MRCP (UK) Specialty Registrar in Diabetes and Endocrinology, Sunderland Royal Hospital, Sunderland. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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