Document Detail

Severe reactions to cow's milk in very young infants at risk of atopy.
MedLine Citation:
PMID:  8871739     Owner:  NLM     Status:  MEDLINE    
Cow's milk (CM) allergy (CMA) is a disease of infancy, usually appearing in the first months of life. Symptoms triggered by CM at first introduction are not completely defined. The aim of this study was to investigate the prevalence of severe reaction to CM and clinical manifestation triggered by CM administration in the first few months of life. Particularly sensitizing appears to be the exposure to CM formulas in the neonatal nursery. The little doses of allergens are more sensitizing than larger ones. These data provide clear evidence of the immunological effects of oral antigen administration during the neonatal period. Babies at risk of atopy should receive in their first days colostrum and/or formulas appropriate for atopy prevention. In this prospective study, we evaluated 27 babies in order to ascertain the prevalence of CM-induced severe reactions.
A Cantani; D Gagliesi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Allergy and asthma proceedings : the official journal of regional and state allergy societies     Volume:  17     ISSN:  1088-5412     ISO Abbreviation:  Allergy Asthma Proc     Publication Date:    1996 Jul-Aug
Date Detail:
Created Date:  1997-01-03     Completed Date:  1997-01-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9603640     Medline TA:  Allergy Asthma Proc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  205-8     Citation Subset:  IM    
Department of Pediatrics, University La Sapienza, Rome, Italy.
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MeSH Terms
Age of Onset
Child, Preschool
Hypersensitivity, Immediate / epidemiology,  etiology*,  physiopathology
Immunoglobulin E / analysis
Milk / adverse effects*
Patch Tests
Prospective Studies
Risk Factors
Reg. No./Substance:
37341-29-0/Immunoglobulin E

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