Document Detail

Severe psittacosis during pregnancy and suppression of antibody response with early therapy.
MedLine Citation:
PMID:  8588147     Owner:  NLM     Status:  MEDLINE    
A cluster of 3 cases of psittacosis occurred among members of one family. The initial case was a pregnant woman who presented with extensive multilobar infiltrates and severe respiratory distress necessitating mechanical ventilation. Her respiratory failure worsened during 36 h of erythromycin therapy. Improvement coincided with the termination of pregnancy and the initiation of doxycycline treatment. The remaining patients developed milder illness. Serologic assessment of the affected subjects suggests that early treatment may suppress antibody response.
R Khatib; M C Thirumoorthi; B Kelly; K J Grady
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Scandinavian journal of infectious diseases     Volume:  27     ISSN:  0036-5548     ISO Abbreviation:  Scand. J. Infect. Dis.     Publication Date:  1995  
Date Detail:
Created Date:  1996-03-27     Completed Date:  1996-03-27     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0215333     Medline TA:  Scand J Infect Dis     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  519-21     Citation Subset:  IM    
Department of Obstetrics and Gynecology, St John Hospital and Medical Center, Detroit, Michigan, USA.
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MeSH Terms
Animals, Domestic / microbiology
Anti-Bacterial Agents / therapeutic use*
Antibodies, Bacterial / biosynthesis
Birds / microbiology
Child, Preschool
Chlamydophila psittaci / immunology
Doxycycline / therapeutic use*
Pregnancy Complications, Infectious / drug therapy*,  immunology
Psittacosis / complications*,  drug therapy*,  transmission
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Antibodies, Bacterial; 564-25-0/Doxycycline

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