| Severe pruritus should be a B-symptom in Hodgkin's disease. | |
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MedLine Citation:
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PMID:Â 6831358 Â Â Â Owner:Â NLM Â Â Â Status:Â MEDLINE Â Â Â |
Abstract/OtherAbstract:
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Pruritus was evaluated with respect to frequency, intensity, and prognostic significance in 360 patients with Hodgkin's disease. In order to discriminate severe from mild pruritus, the following criteria was used: (1) multiple excoriations; (2) ineffectiveness of local and systemic antipruritics; and (3) improvement with either radiotherapy or chemotherapy. Ninety of 360 patients had mild itching on admission and showed the same survival as the 249 nonitching cases; 21 patients presented with severe pruritus, which was also generalized, and showed a statistically shorter survival than that of mild and non-itching cases. This comparison was carried out between patients homologous with respect to sex, age, stage, A or B category, and histotype. Analysis of the data pointed out that the third requirement, i.e., improvement with antineoplastic therapy, is not substantial; moreover, for staging purposes, it is preferably replaced by the requisite of generalized pruritus. The intrinsically poor prognosis related to severe pruritus may be important for treatment, when this symptom occurs in early stages or without other systemic symptoms. The inclusion of severe pruritus among the Ann Arbor criteria for definition of the B-clinical category is proposed. |
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Authors:
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P G Gobbi; G Attardo-Parrinello; G Lattanzio; S C Rizzo; E Ascari |
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Publication Detail:
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Type: Journal Article    |
Journal Detail:
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Title: Cancer    Volume: 51    ISSN: 0008-543X    ISO Abbreviation: Cancer    Publication Date: 1983 May |
Date Detail:
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Created Date:Â 1983-05-27 Â Â Â Completed Date:Â 1983-05-27 Â Â Â Revised Date:Â 2004-11-17 Â Â Â |
Medline Journal Info:
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Nlm Unique ID: 0374236    Medline TA: Cancer    Country: UNITED STATES    |
Other Details:
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Languages: eng    Pagination: 1934-6    Citation Subset: AIM; IM    |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Female Hodgkin Disease / complications* Humans Male Middle Aged Prognosis Pruritus / etiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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