| Severe primary hypothyroidism presenting with torsades de pointes. | |
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MedLine Citation:
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PMID: 22987900 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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An 85-year-old lady presented to our institution following multiple episodes of transient loss of consciousness. Her admission ECG revealed a junctional bradycardia with significant QT prolongation. Telemetry captured a torsades de pointes arrhythmia. Possible offending drugs (digoxin and hydroxychloroquine) were stopped and she was given intravenous magnesium and potassium. Despite this, she continued to have runs of torsades. An isoprenaline infusion was commenced to increase her resting heart rate. Her QT interval shortened and she had no further arrhythmia. Investigation into the cause of her bradycardia and prolonged QT revealed profound hypothyroidism. Levothyroxine was commenced but the patient remained bradycardia and required a permanent pacemaker. She had no further arrhythmia and was discharged home safely. This is a very rare case of severe primary hypothyroidism presenting with torsades de pointes. |
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Authors:
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Sri Raveen Kandan; Mrinal Saha |
Publication Detail:
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Type: Journal Article Date: 2012-09-17 |
Journal Detail:
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Title: BMJ case reports Volume: 2012 ISSN: 1757-790X ISO Abbreviation: BMJ Case Rep Publication Date: 2012 |
Date Detail:
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Created Date: 2012-09-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101526291 Medline TA: BMJ Case Rep Country: England |
Other Details:
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Languages: eng Pagination: - Citation Subset: IM |
Affiliation:
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Gloucestershire Royal Hospital, Gloucester, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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