| Severe preeclampsia in antithrombin III deficiency with no history of venous thromboembolism. | |
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MedLine Citation:
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PMID: 11506257 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Complications of pregnancy, such as preeclampsia, placental abruption, fetal growth retardation, still-birth and fetal death are associated with an increased frequency of pro-thrombotic abnormalities. We describe a case of severe preeclampsia and multiple placental infarctions in a 28-year-old woman at 31 weeks' gestation. Despite a negative personal history for venous thromboembolism, coagulation screening for thrombophilia detected an isolated antithrombin III deficiency. In view of the high prevalence of pro-thrombotic complications, laboratory screening for thrombophilia would be advantageous in women with complicated pregnancies, to ensure adequate management in high-risk situations, as suggested by larger-scale clinical investigations. |
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Authors:
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L Gammaro; G Lippi; E Bottini; G Valenti; F Manzato; N Tessitore; G Maschio |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of nephrology Volume: 14 ISSN: 1121-8428 ISO Abbreviation: J. Nephrol. Publication Date: 2001 Jul-Aug |
Date Detail:
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Created Date: 2001-08-16 Completed Date: 2002-08-01 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9012268 Medline TA: J Nephrol Country: Italy |
Other Details:
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Languages: eng Pagination: 312-5 Citation Subset: IM |
Affiliation:
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Division of Nephrology, Verona Hospital, Italy. lgammaro@interfree.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antithrombin III Deficiency / complications* Female Humans Pre-Eclampsia / etiology* Pregnancy Pregnancy Complications, Hematologic* Severity of Illness Index |
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