Document Detail

Severe preeclampsia and fetal virilization in a spontaneous singleton pregnancy complicated by hyperreactio luteinalis.
MedLine Citation:
PMID:  22338557     Owner:  NLM     Status:  MEDLINE    
CASE REPORT: A 24-year-old pregnant woman, G3 P0, who was admitted to the Perinatology Clinic with increasing findings of virilization during pregnancy was presented. The patient had bilaterally enlarged multicystic ovaries on sonographic examination and elevated serum androgen levels She was managed conservatively until 38th week of gestation as a presumptive diagnosis of hyperreactio luteinalis. Elevated blood pressure and prominent proteinuria were detected during the follow-up of the patient and labor was induced. She underwent an emergency caesarean delivery because of fetal distress. During caesarean section, ovarian biopsies were taken and a histopathological diagnosis of hyperreactio luteinalis was determined. The female fetus also presented virilization.
CONCLUSION: Although infrequent, hyperreactio luteinalis with both maternal and fetal virilization can occur in women with spontaneous singleton pregnancies. The clinical manifestations in such women may be complicated by severe preeclampsia.
Y Simsek; S Celen; Y Ustun; N Danisman; H Bayramoglu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European review for medical and pharmacological sciences     Volume:  16     ISSN:  1128-3602     ISO Abbreviation:  Eur Rev Med Pharmacol Sci     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-02-17     Completed Date:  2012-03-12     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  9717360     Medline TA:  Eur Rev Med Pharmacol Sci     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  118-21     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Inonu University Faculty of Medicine, Malatya, Turkey.
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MeSH Terms
Androgens / blood
Cesarean Section / adverse effects
Infant, Newborn
Lutein / metabolism*
Ovarian Cysts / complications,  metabolism*,  pathology
Pre-Eclampsia / pathology*
Virilism / pathology*
Young Adult
Reg. No./Substance:
0/Androgens; 127-40-2/Lutein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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