| Severe pertussis in infants: estimated impact of first vaccine dose at 6 versus 8 weeks in australia. | |
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MedLine Citation:
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PMID: 20811313 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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We estimated the potential benefits of advancing the first dose of pertussis vaccine for infants from 8 to 6 weeks of age, using Australian national disease databases. Infants had notification rates 3-fold greater than the general population and accounted for 52% of recorded hospitalizations. Infants 1 and 2 months of age had notification rates 3.5 times (95% CI: 2.7-4.5) higher than infants 3 to 11 months of age. Estimation of acceleration of the vaccine to 6 weeks of age reduced average notifications, hospitalizations, and hospital bed-days by 8%, 9%, and 12%, respectively, with larger reductions in an epidemic year. |
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Authors:
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Alice Ruth Foxwell; Peter McIntyre; Helen Quinn; Katrina Roper; Mark S Clements |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Pediatric infectious disease journal Volume: 30 ISSN: 1532-0987 ISO Abbreviation: Pediatr. Infect. Dis. J. Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-01-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8701858 Medline TA: Pediatr Infect Dis J Country: United States |
Other Details:
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Languages: eng Pagination: 161-3 Citation Subset: IM |
Affiliation:
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From the *Communicable Disease and Surveillance Branch, Office of Health Protection, Department of Health and Ageing, Australian Government, Canberra, Australia; †National Centre for Epidemiology and Population Health, Australian National University, Canberra, Australia; and ‡National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases, The Children's Hospital at Westmead and the University of Sydney, Sydney, Australia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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