Document Detail


Severe peripartum sepsis.
MedLine Citation:
PMID:  22184573     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Despite global efforts to reduce maternal mortality, maternal deaths from bacterial sepsis have actually risen in the UK. The group A streptococcus, also known as Streptococcus pyogenes, is the leading cause of infection-related death in pregnancy and the puerperium. Many clinicians remain unaware of the risks posed to this particular group of otherwise fit, healthy patients despite the fact that S. pyogenes has been the leading infective cause of puerperal deaths since records began. S. pyogenes has a specific but unexplained predilection for the recently pregnant woman, and has an attributable mortality greater than many other invasive bacteria. Here, the epidemiology, aetiology, and management of severe peripartum sepsis are discussed, as are potential approaches to reduce risks. While fundamental changes in healthcare access can lead to dramatic reductions in maternal deaths in developing countries, an improvement in maternal sepsis deaths in the UK will require heightened awareness among both hospital and community-based clinical staff.
Authors:
S Sriskandan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The journal of the Royal College of Physicians of Edinburgh     Volume:  41     ISSN:  2042-8189     ISO Abbreviation:  J R Coll Physicians Edinb     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101144324     Medline TA:  J R Coll Physicians Edinb     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  339-46     Citation Subset:  IM    
Affiliation:
National Centre for Infection Prevention and Management, Department of Infectious Diseases & Immunity, Imperial College London, Hammersmith Campus, Du Cane Road, London W12 0NN, UK. s.sriskandan@imperial.ac.uk.
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