Document Detail


Severe oligoasthenoteratozoospermias, secretory and obstructive azoospermias: motility as a criterion of sperm viability.
MedLine Citation:
PMID:  17450432     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: Comparison of pregnancy rates in cases of Secretory Azoospermias (SA), Obstructive Azoospermias (OA) and severe Oligoasthenoteratozoospermias (OATZ). Evaluation of sperm motility as a quality criterion.
METHODS: In SA cases (n = 35), 9 samples were cryopreserved. In OA cases (epididymal aspiration: n = 91; testicular biopsy: n = 206), all samples were cryopreserved. 596 OATZ ejaculates were included.
RESULTS: In SA cases, 2 pregnancies were achieved from 9 ICSI cycles. In OA, motile sperm rates were higher in testicular biopsies. After thawing sperm motility was not different between testicular and epididymal origin. 2 pregnancies were achieved with immotile testicular sperm after thawing, but none with immotile epididymal sperm. In OATZ cases, one pregnancy was obtained from the 9 cryopreserved ejaculates and 35.3% with fresh motile sperm.
CONCLUSIONS: In SA cases, the use of donor sperm is recommended due to the lower pregnancy rate achieved. Motility, before and after cryopreservation, as a criterion of sperm viability is discussed and its use should be reconsidered in some cases.
Authors:
I Molina; J Alfonso; C C Duque; L García-Reboll; M Pérez-Camps; A Romeu
Publication Detail:
Type:  Journal Article     Date:  2007-02-16
Journal Detail:
Title:  Journal of assisted reproduction and genetics     Volume:  24     ISSN:  1058-0468     ISO Abbreviation:  J. Assist. Reprod. Genet.     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-04-23     Completed Date:  2007-09-12     Revised Date:  2013-03-27    
Medline Journal Info:
Nlm Unique ID:  9206495     Medline TA:  J Assist Reprod Genet     Country:  United States    
Other Details:
Languages:  eng     Pagination:  125-9     Citation Subset:  IM    
Affiliation:
Human Assisted Reproduction Unit, La Fe University Hospital of Valencia, Valencia, Spain. molina_inmbot@gva.es
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MeSH Terms
Descriptor/Qualifier:
Azoospermia / pathology,  physiopathology*
Biopsy
Cell Survival
Cryopreservation
Ejaculation
Epididymis / pathology
Female
Humans
Male
Oligospermia / pathology,  physiopathology*
Pregnancy
Pregnancy Outcome
Sperm Injections, Intracytoplasmic
Sperm Motility*
Spermatozoa / cytology*
Testis / pathology
Comments/Corrections

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