Document Detail

Severe mitral regurgitation due to cardiac amyloidosis--a rare reason for ruptured chordae.
MedLine Citation:
PMID:  18755788     Owner:  NLM     Status:  MEDLINE    
Although cardiac amyloidosis is often associated with mitral valve disease due to amyloid deposits, severe mitral valve regurgitation in a patient with systemic amyloidosis is uncommon. We report a 38-year-old man with severe mitral valve regurgitation due to ruptured chordae. He underwent mitral valve repair and both leaflets of mitral valve appeared normal except for ruptured chordae. Postoperative histological results revealed the presence of the amyloid deposit in the mitral valve and ruptured chordae. The amyloid deposit might be a cause of ruptured chordae, which is a rare reason for mitral valve regurgitation in a patient with cardiac amyloidosis.
Hiroyuki Nishi; Masataka Mitsuno; Masaaki Ryomoto; Yuji Miyamoto
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-08-28
Journal Detail:
Title:  Interactive cardiovascular and thoracic surgery     Volume:  7     ISSN:  1569-9285     ISO Abbreviation:  Interact Cardiovasc Thorac Surg     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-11-25     Completed Date:  2009-01-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101158399     Medline TA:  Interact Cardiovasc Thorac Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  1199-200     Citation Subset:  IM    
Department of Cardiovascular Surgery, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.
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MeSH Terms
Amyloidosis / complications*,  pathology,  surgery
Cardiomyopathies / complications*,  pathology,  surgery
Chordae Tendineae*
Heart Rupture / etiology*,  pathology,  surgery
Heart Valve Prosthesis Implantation
Mitral Valve Insufficiency / etiology*,  pathology,  surgery
Serum Amyloid A Protein / analysis
Severity of Illness Index
Treatment Outcome
Reg. No./Substance:
0/Serum Amyloid A Protein

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