Document Detail

Severe lead poisoning in the plastics industry: a report of three cases.
MedLine Citation:
PMID:  15662640     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Lead stabilizers (e.g., lead sulfate, lead stearate) are common additives in plastics used in electrical devices. In 1997, three plastics compounders at one California company were severely lead-poisoned. METHODS: The poisonings were investigated by interviewing the workers, employer, and treating physician and reviewing medical records and environmental monitoring results. In addition to measuring blood lead levels (BLLs), noninvasive K X-ray fluorescence was used to measure bone lead concentration of the index case. RESULTS: Blood lead concentrations of the three workers at time of diagnosis were 159, 114, and 108 microg/dl. The worker with highest exposure presented with clinical findings of crampy abdominal pain, constipation, normocytic anemia, fatigue, and reversible azotemia. Bone lead concentration in his tibia, calcaneous, and patella were 102, 219, and 182 ppm, respectively. The poisonings resulted from uncontrolled use of powdered lead sulfate stabilizer. CONCLUSION: Clinicians should be aware of potential serious overexposure to lead in compounding of plastics.
Patricia Coyle; Michael J Kosnett; Karen Hipkins
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of industrial medicine     Volume:  47     ISSN:  0271-3586     ISO Abbreviation:  Am. J. Ind. Med.     Publication Date:  2005 Feb 
Date Detail:
Created Date:  2005-01-26     Completed Date:  2005-04-12     Revised Date:  2006-02-27    
Medline Journal Info:
Nlm Unique ID:  8101110     Medline TA:  Am J Ind Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  172-5     Citation Subset:  IM    
Occupational Health Branch, California Department of Health Services, Oakland, California 94612, USA.
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MeSH Terms
Abdominal Pain / chemically induced
Kidney Failure / chemically induced
Lead / toxicity*
Lead Poisoning / blood,  etiology*,  prevention & control
Occupational Diseases / chemically induced*,  prevention & control
Plastics / chemistry*
Reg. No./Substance:
0/Plastics; 7439-92-1/Lead; 7446-14-2/lead sulfate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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