Document Detail

Severe intrauterine growth restriction associated with the development of a submucosal leiomyoma during pregnancy: a case report.
MedLine Citation:
PMID:  16130857     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Small, intramural leiomyomas are not generally considered a risk factor for poor reproductive outcomes. CASE: A patient with a 6-mm intramural leiomyoma and a normal uterine cavity by hysteroscopic evaluation who conceived after in vitro fertilization developed severe early-onset intrauterine growth restriction (IUGR), leading to pregnancy termination at 23.4 weeks' gestation. At 6 weeks postpartum, a 1.7-cm, intracavitary leiomyoma was detected on ultrasound evaluation and removed by hysteroscopic resection. The patient conceived in a subsequent in vitro fertilization cycle and gave birth to monozygotic twins with appropriate weights at 34 weeks of gestation. In the absence of other identifiable etiologies of the IUGR, it is plausible that the small, intramural leiomyoma enlarged and migrated into the cavity, causing abnormal placentation and leading to fetal growth restriction in the first pregnancy. CONCLUSION: Uterine cavity reevaluation is recommended in the investigation of IUGR before a woman attempts further pregnancies.
Natali Aziz; Tiffanee A Lenzi; Amin A Milki
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  50     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  2005 Jul 
Date Detail:
Created Date:  2005-08-31     Completed Date:  2006-02-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  553-6     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California 94305, USA.
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MeSH Terms
Abortion, Induced
Fertilization in Vitro
Fetal Growth Retardation / etiology*,  ultrasonography
Leiomyoma / complications*,  surgery,  ultrasonography
Ultrasonography, Prenatal
Uterine Neoplasms / complications*,  surgery,  ultrasonography

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